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Risk reduction of respiratory symptoms.
Clinical Study ResultsShow DuPont Probiotics Reduce Risk of Respiratory Symptoms in
Healthy Adults Clinical Nutrition Publishes New Study that Demonstrates the Immune Health Benefits of HOWARU® Protect.
KANTVIK, Finland, Oct. 23, 2013 — DuPont Nutrition & Health
welcomes new clinical evidence on the impact of DuPont™
Danisco® HOWARU® Protect probiotics in helping to maintain
respiratory health for healthy adults. Investigated in a joint clinical
study by Australian research institutes, two probiotic formulations
were seen to reduce the risk of and delay the onset of respiratory
illness, and to improve training load during physical exercise.
The study titled, “Probiotic supplementation for respiratory
and gastrointestinal illness symptoms in healthy physically
active individuals,” was just published in Clinical Nutrition, the
official journal of the European Society for Clinical Nutrition and
Metabolism. It is available online at: www.clinicalnutritionjournal.
com (publication), www.clinicalnutritionjournal.com/article/S0261-
Gold Standard Trial
Scientists from Griffith University conducted the randomized,
double-blind, placebo controlled clinical trial in cooperation
with the Australian Institute of Sport and other collaborating
institutions. The 465 trial subjects were split into three groups,
each receiving a daily dose of HOWARU® Protect Adult,
HOWARU® Protect Sport or a placebo. All subjects were healthy
adults who exercised for at least 30 minutes, three times per
Risk of Cold-Like Symptoms Reduced 27 Per cent
Daily supplementation with Bifidobacterium animalis subsp. lactis
Bl-04TM – known commercially as HOWARU® Protect Adult –
produced the most notable result. In the healthy men and women
who consumed a daily dose over the five-month study period, the
risk of upper respiratory tract illness (URTI) was reduced by 27 per
The results also indicate that Bl-04™ supports respiratory
health, with trial subjects remaining free of upper respiratory
symptoms for several weeks longer, on average, than those in the
“A significant delay in the onset of symptoms indicates that
this probiotic strain may help active adults stay healthy longer,”
said Professor Allan Cripps, pro-vice chancellor, Health at Griffith
University and the principal scientist of the study.
Increased Physical Activity
A tendency toward reduced respiratory illness episodes and
significant delay in the onset of symptoms also was observed
among subjects who received the other probiotic formulation –
Bifidobacterium animalis subsp. lactis Bi-07TM and Lactobacillus
acidophilus NCFM®, available from DuPont as HOWARU® Protect
Sport. The most notable finding in this group, however, was a
significantly higher level of physical activity, possibly due to the
delayed time to symptoms.
“It is a known fact that physical activity is reduced or may
even stop when people are feeling the effects of respiratory
symptoms. So, these findings are important, particularly for those
who engage in competitive sports and need to maintain fitness,”
said Professor David Pyne, senior physiologist at the Australian
Institute of Sport and lead investigator of the study.
“These results reinforce our existing documentation on probiotic
solutions for immune health and open new opportunities for the
HOWARU® Protect range,” said Didier Carcano, health platform
leader, DuPont Nutrition & Health.
DuPont™ Danisco® is the brand for a range of ingredients
that help provide enhanced bioprotection, an improved
nutritional profile, and better taste and texture with greater cost
efficiency and lower environmental impact, meeting the needs
of manufacturers of food and beverages, dietary supplements
and pet food. Through the work of the global network of food
scientists and technologists in DuPont, the Danisco® range is
supported by a uniquely broad spectrum of know-how across
applications and processing. For more information on DuPont™
Danisco®, go to: www.danisco.com.
DuPont Nutrition & Health addresses the world’s challenges
in food by offering a wide range of sustainable, bio-based
ingredients and advanced microbial diagnostic solutions to
provide safer, healthier and more nutritious food. Through close
collaboration with customers, DuPont combines knowledge and
experience with a passion for innovation to deliver unparalleled
customer value to the marketplace.
DuPont (NYSE: DD) has been bringing world-class science and
engineering to the global marketplace in the form of innovative
products, materials, and services since 1802. The company
believes that by collaborating with customers, governments,
NGOs and thought leaders, we can help find solutions to
such global challenges as providing enough healthy food for
people everywhere, decreasing dependence on fossil fuels, and
protecting life and the environment. For additional information
about DuPont and its commitment to inclusive innovation, please