Research has demonstrated that glutamine stimulates muscle synthesis, aiding muscle repair following strenuous exercise. Glutamine is increasingly used in sports nutrition supplements as scientists’ understanding of the advantages of providing supplementary amino acids grows, and as consumer awareness of the benefits increases.

In Japan, where the market was pioneered, products with amino acids have helped the sports drinks sector to gain a 10 per cent share of the beverage market. Amino Vital, a sports drink with amino acids, has recently been launched in the United States and demand looks set to extend to Europe where the sports nutrition industry is growing rapidly. In 2005, United Kingdom sales of sports nutrition products reached £180 million with analysts predicting that the market will grow a further 30 per cent by 2010.

The factory in Brazil is one of the world’s largest amino acid production facilities, helping Ajinomoto consolidate its position as the leading amino acids manufacturer. As well as glutamine, the new plant will also produce the branched-chain amino acids valine, leucine and isoleucine.

The Ajinomoto Group, which holds a 60 per cent share of the market in pharmaceutical and nutritional amino acids, has increased capacity in response to rising global demand for amino acids. Ajinomoto employs advanced biocatalytic technology to synthesise glutamine. The ingredient is produced in a fermentation process by which enzymes convert a source of carbohydrate into glutamine. This technique ensures both the purity and quality of Ajinomoto Glutamine.

Amino Vital, targeted at athletes and marketed by Ajinomoto in Japan and the United States, contains glutamine.

Amino Vital, targeted at athletes and marketed by Ajinomoto in Japan and the United States, contains glutamine.

New Ajinomoto Glutamine factory in Limeira, Brazil

The non-randomized Phase I open label clinical study, entitled “Evaluation of the effect of Neptune Krill Oil (NKO™) on Attention Deficit Hyperactivity Disorder (ADHD)”, was initiated by the International Organization of ADHD and conducted by Barry University in Miami Shores, FL, USA and private naturopath Clinics in Montreal, Quebec, Canada.

The objective of the study was to evaluate the effect of NKO™ on adult ADHD as measured by Barkley’s Executive Function score of behaviour inhibition, daily functional capacity and social behaviour. Thirty (30) otherwise healthy adults with a confirmed diagnosis of ADHD taking a 500mg daily dose of NKO™ were originally enrolled in the study of whom 25 (83.3%) completed 6 months of treatment. The five (16.7%) patients who did not complete the study were lost in follow-up. No adverse events were reported amongst the 30 patients recruited at baseline during the course of their treatment.

After 6 months of treatment the 25 patients who completed the study showed a statistically significant improvement in all Barkley’s Executive Function scores. In particular, patients improved their ability to concentrate and their working capacity by 60.2% (p<0.001), their social skills by 48.8% (p<0.001), their ability to manage money by 34.2% (p=0.004), their driving capacity and road-safety skills by 34.5% (p=0.011), their ability to focus by 39.0% (p<0.001) and their planning skills by 50% (p=0.001).

“I am extremely happy with these results. It is great to have tangible evidence of the significant beneficial effect of NKO™ on cognition” said Tina Sampalis, M.D., Ph.D., Vice President of R&D and Business Development at Neptune. “Based on these encouraging results we will now proceed to the initiation of a pivotal Phase II/III clinical program on cognitive function.”

“We are all very happy that we had the opportunity to participate in the study of such a promising product. Neptune Krill Oil (NKO) is shown to be a natural, safe and effective product for the treatment of ADHD.” said Dr. Leslie Rouder, Director of Disability Services at Barry University, Florida, USA and Private Practitioner specializing in adult ADHD. “We are looking forward to implementing NKO in ADHD management” she added.

“ADHD is a disorder where biological vulnerability meets environmental influences. Drugs are useful resources in the treatment of ADHD but medication is not always the best answer: over prescription, drug induced toxicity and the high cost of treatment are recognized problems of the recommended ADHD management guidelines. NKO™ will help patients reduce or even avoid medication and improve their quality of life” said Dr Marius Gangal, MD, PhD, MBA, who recently joined Neptune as Medical Director.

Dr Marius Gangal is an experienced neuro-pathologist with a strong medical research practice on cognitive disorders and neurodegenerative pathology, previous Medical Consultant of Cytochem and Research Associate of the Research Center of the University Hospitals of Montreal (Centre de Recherche CHUM).

The cost of treatment of adult ADHD is estimated for United States alone at $15.3 billion per year. Between 4 -12% of children and 1-6% of the adult North American population are diagnosed with ADHD. According to Birnbaum et al (Curr Med Res Opin. 2005 21(2):195-205), in the year 2000, the total cost of ADHD in the US was $31.6 billion. Of this, $1.6 billion was for ADHD treatment of patients, $12.1 billion was for all other healthcare costs of persons with ADHD, $14.2 billion was for all other healthcare costs of family members of persons with ADHD and $3.7 billion was for the work loss of adults with ADHD and adult family members of persons with ADHD. In reality ADHD affects 54% of women and 36% of men with adult ADHD that also suffer from major depression.

About Neptune Technologies & Bioressources Inc. http://www.neptunebiotech.com

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For example a research or sales director may need a half day workshop in say regulatory affairs on novel foods, but can only find that training facility at a conference that maybe is months ahead and that would also cover issues that he or she is not interested in. Our differentiation is that we can provide the training at short notice and at a date and time that suit’s the persons schedule and tailored especially to suit their specific needs. We can undertake the workshop or seminar at the client’s hotel or their companies headquarters. We can also provide the training over the internet via powerpoint and skype / MSN messenger services, or they can attend our conference facilities near Stansted airport in the UK which can also include overnight accommodation, wifi access and hospitality. The point is that we offer flexibility plus fast and efficient training. The list of topics include how to get regulatory approval, analysis and extraction of botanicals, undertaking clinical trials, forming strategic partnerships in the EU, business to business marketing, how to get media attention for products & associated PR, and even how to set up an international consultancy business in nutraceuticals among others! We can offer these services because we do this kind of work all the time, are very experienced at training including ten years within the University system and also by conducting numerous conference papers and industry seminar sessions over the past ten years on an international basis. These include training sessions at Supply Side West, Las Vegas, USA; Natural Products Show, Holland; Vitafoods, Geneva; Active Ingredients Conference, Paris; Supply Side East, Baltimore USA; ABARE conference, Australia; and many others.

Dr Tony Evans, previous President of Valensa Inc, specialising in supercritical extracts for the nutraceutical industry based in Florida, USA commented “Dr Wilkinson is certainly an accomplished lecturer and has given excellent presentations on our behalf to our strategic marketing partners in Europe as well as conducting industry seminars for us at Vitafoods in Geneva and SSW in Las Vegas. Herbal Sciences delivers seminars that are concise, articulate and often delivered with a liberal amount of humour”

Cyril Lombard, Market Development Manager at Phytotrade Africa, a trade association representing some 58 members in 8 countries in southern Africa and specialising in supplying African botanicals to the nutraceutical and other industries said “Dr Wilkinson has provided some excellent industry seminars on our products at international conferences and seminars. He and his team provide the right balance of scientific, regulatory and commercial expertise, and communicate this exceptionally well. Their service is highly tailored to our specific requirements, and can be conceived, implemented and reported on in very tight timeframes. For example, last year his company did some biological studies for us on Kigelia africana. They were started in February and finished, written up and presented at Vitafoods in May of that year, which is actually very impressive! We plan to get Herbal Sciences to provide a specific one day seminar on the extraction of botanicals, among others, in the future.

For further information see: http://www.herbalsciencesinternational.com/productssimple4.html

The new blend is part of the Danisco Kefir range based on real freeze-dried kefir grains, that are coming
with a long list of reputed health benefits, yeasts and lactic cultures to provide various textures and
flavour intensity.
In addition to the kefir shot presented at the HIE, Danisco developed five appealing and trendy
kefir formulations from a traditional Snow Rose kefir as Known from centuries to other differentiating possibilities with Lemon Cooler, Strawberry Sensation, Oriental Delight or Apple Blossom.
“Our new kefir formulations provide not only a unique refreshing sensation but also an extended
shelf life compared to traditional kefir reaching up to 21 days”, says Jana Parn, M.Sc., Dairy
Application Specialist.
Thanks to its light fizziness, nutty flavour and Caucasian origins, kefir is spreading from its
traditional roots in Eastern and Central Europe, where it represents 1,2 million tons*, to other
regions, opening up a world of opportunities.
HOWARU™ is a registered trademark of Danisco A/S
* Danisco estimates

New product developments in 2006-2007 include Solbar’s Contex 31-AR textured soy concentrate designed for pasteurized meat products unique to China. The prototype of Contex AR is product code number 31, an 8 mm flake characterized by very high water absorption and water holding capacity. Contex 31-AR is colored using a proprietary pinkish red color that matches typical Chinese pork products. Contex AR increases protein content and improves mouthfeel, at significant costs reductions to meat manufacturer. In combination with Solcon S-110, S-116 and S-188, manufacturers are finding an ideal functional solution to meat processing. Solbar’s is committed to providing the food industry with critical natural soy solutions.

At the Fi China, Solbar will offer its entire range of soy proteins and invites visitors to learn more about the advantages of soy in the daily diet.

For further information, please contact:

Gary Brenner
Solbar Plant Extracts Ltd
T: +97288632111
F: +97288561455
spe@solbar.com

This product was developed to answer to the desire of customers to avoid the use of any materials possibly linked with genetically modified organisms in their processes, i.e. manufacturing of food or food related products.

Noviant produce the Nymcel range in a state-of-the-art facility in The Netherlands which complies with all modern standards for production of food additives (Cekol ®) and pharmaceutical excipients (Cekol ® and Nymcel ®). The manufacturing method offers complete transparency and traceability.

The Nymcel range offers the following unique features:

• Consistent quality and supply
• Consistent and stable pricing
• Low dosage rate
• Suitable for dry granulation
• Suitable for wet granulation
• Suitable for direct compression